Found 39 matching trials
A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100) PHASE1 Evaluate the safety and tolerability of sotorasib in adult subjects with KR...
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City of Hope National Medical Center
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Drug-drug Interaction Study of Gepotidacin PHASE1 This study is a drug-drug interaction (DDI), pharmacokinetics (PK), safety ...
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GSK Investigational Site
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A Study to Investigate the Effect of GSK1605786 on Hepatic Cytochrome P450, and BCRP and OATP1B1 Transport in Healthy Adult Subjects PHASE1 The purpose of this study is to test the effects of study drug (GSK1605786)...
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GSK Investigational Site
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Study to Evaluate the Effect of Delafloxacin on the Pharmacokinetics of Midazolam in Healthy Subjects PHASE1 The purpose of this study is to evaluate the effect of repeated doses of or...
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PPD Development, LP
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Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients PHASE1 To study the Pharmacokinetics (PK) parameters of montelukast, flurbiprofen,...
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Multiple Locations
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Effects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and Midazolam PHASE1 This is an open-label, multi-center, fixed sequence study in subjects with ...
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GSK Investigational Site
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Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy NA This study aims to compare the efficacy of using oral Melatonin versus nebu...
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Pharmacokinetic Interaction of Darapladib and CYP 3A4 in Healthy Subjects PHASE1 This study will determine the effect of single and repeat administration of...
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GSK Investigational Site
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Safety, Tolerability and Pharmacokinetics of FTX-6058 PHASE1 This is a study to evaluate the safety, tolerability and pharmacokinetics o...
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Atlanta Center for Medical Research - Sickle Cell Subjects Only
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Effects of Oral Midazolam in Comparison Promethazine With Nitrous Oxide for Uncooperative Children PHASE3 The purpose of this study is to compare the safety and efficacy of sedation...
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Dental school of Shahid Beheshti University of Medical Sciences
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